Three werewolf women from Uranus travel to Earth to rid New York City of the terrible people – sexists, stooges and bullies. Once inside the city, they must face off against clueless art critics (Janeane Garofalo and Dave Hill), religious fanatics, and capitalist corporate suits – with a little help from their new local friends, including bumbling officers Fremulum and Hymen, a teenage girl Candy (Rachel Trachtenburg), and one crazy drunkard. Together they will stand against the evils of New York City!